For comparison, staining for the protein Tau, long known to be involved in Alzheimer's and other neurodegenerative diseases. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy ...

Researchers discovered a connection between Alzheimer’s disease and herpes simplex virus-1 (HSV-1), suggesting viral ...

Alzheimer's disease (AD), the most common cause of dementia, has a strong genetic basis, with heritability estimates ranging from 60% to 80%. While hallmark features like tau tangles and amyloid ...

The pathological hallmarks of Alzheimer's disease (AD) are amyloid-β (Aβ) plaques and Tau-containing neurofibrillary tangles. Although the relationship between neuronal loss and the presence of ...

This study examined whether sex, age, microglial activation or ApoE4 modulates the Aβ to p-tau axis, a critical event in the ...

The inflammatory response can affect the tau pathological metamorphosis, increasing tau phosphorylation via MAPK kinase pathways and accelerating tangle formation. Extracellular tau can induce ...

Ke Hou generated a compound that prevents tau aggregation in the murine brain, but the potential Alzheimer’s disease therapy ...

The oral herpes virus appears to be linked with Alzheimer’s disease, suggesting that the common infection might play a role ...