The Lions will face a 49ers offensive line that could be starting two tackles signed off practice squads this week ...

San Francisco 49ers top scorers look to capitalize on opportunities early against Detroit Lions stout defense.

The San Francisco 49ers find themselves out of the playoff race just one season removed from a Super Bowl appearance, leaving ...

Judges declare the 2020 conviction of the former NFL Defensive Player of the Year is ‘legally invalid’ after finding his race ...

The Detroit Lions and San Francisco 49ers met 11 months ago at Levi's Stadium with a trip to the Super Bowl on the line. San Francisco used a furious second half comeback to steal the NFC Championship ...

Find out what the San Francisco 49ers are saying as they prepare for their Week 17 matchup vs. the Detroit Lions.

NFL Week 17 odds, picks, predictions, TV channel, streaming information for Monday Night Football game between Detroit Lions ...

The 49ers just lost 29-17 to the Miami Dolphins. Here are the 49ers' grades for this performance. QUARTERBACK: C Brock Purdy ...

Winters (chest) was a full participant in Thursday's practice. Winters picked up a chest issue in Sunday's loss to Miami, but his ability to practice in full Thursday suggests that he's not ...

The 49ers have made a couple of roster moves, while also shutting down a defensive player for the season’s final two games. San Francisco announced left tackle Trent Williams has been placed on ...