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The US administration has extended its line of attack on academia from US federal research to private universities. The abuse ...

Although student mobility is being restricted in a less dramatic fashion than currently in the USA, the impact on science ...

imageimageIn spermatogenesis, loss of promoter DNA methylation reactivates retrotransposons in patterns shaped by chromatin modifications and the binding of DNA methylation-sensitive transcription ...

Therefore, the aim of this study was to perform an extensive multi-omic analyses on cryopreserved pre-mortem human left ventricular myocardium to uncover the influence of DM in end-stage HF and to ...

Lymphedema is a chronic lymphatic disorder characterized by persistent tissue swelling, pain, and recurrent infections, often secondary to cancer treatment, surgery, or obesity. Obesity-associated ...

imageimageThe ALS-associated VAPB P56S mutation disrupts ER–mitochondria associated membranes (ER-MAMs) and leads to mitochondrial stress and activation of the integrated stress response (ISR). ISR ...

Glioblastoma Multiforme (GBM) is a highly malignant brain cancer with limited effective therapies. Neurodevelopmental pathways have been implicated in glioma formation, with key neurodevelopmental ...

imageimageThis study developed a systematic workflow leveraging transcriptomics and metabolomics to identify input signals for 41 transcription factors in E. coli. A systematic workflow was developed ...

Generating longitudinal and multi-layered big biological data is crucial for effectively implementing artificial intelligence (AI) and systems biology approaches in characterising whole-body ...

imageimageTight control of separase activity is essential for prolonged meiotic arrest of mammalian oocytes. Here, removal of securin and cyclin B1-Cdk1 dual inhibition of separase in mouse oocytes ...