In biology, the binding of cellular proteins to molecules called ligands produces myriad functions essential for life, ...

Proteins, essential macromolecules for biological processes like metabolism and immune response, follow the sequence-structure-function paradigm, where amino acid sequences determine 3D structures and ...

Low-abundance proteins, such as the tau protein in spinal fluid 8 or cytokines ... splice variants, amino acid–relevant single-nucleotide polymorphisms and more than 200 different PTMs.

Researchers from Mainz University and EMBL Hamburg present a new approach to determine the form of disordered proteins by ...

Researchers of Mainz University and EMBL Hamburg present a new approach to determine the form of disordered proteins by using two different methods simultaneously in a single sample.

of sequences fully tailored to the sample's origin, the studied protein features and the experimental technology. Note: Supplementary information is available on the Nature Methods website.

Late-onset Alzheimer's disease is a debilitating, progressive neurodegenerative disease that affects about 7 million ...

VIMs are made up of 266 amino acid residues with the exception of VIM ... in the Lahey Clinic [201], but there are no data and sequence information available.

Proteins are made of strings of amino acids that resemble the strand in the image above. Using machine learning models, researchers were able to design the identity of amino acids on a computer to ...

Tau is a protein that is found in cells of the central nervous system and is involved in the assembly and stabilisation of neuronal microtubules – channels used to transport substances to ...

Tau is a protein that is found in cells of the central nervous system and is involved in the assembly and stabilisation of neuronal microtubules – channels used to transport substances to ...