Research shows 60% of missense mutations destabilize proteins, linking protein folding to genetic diseases, including ...
Proteins are fundamental to life. They are involved in virtually every process within our bodies, from catalyzing chemical ...
Researchers say strategy will help understand the history of life, monitor the spread of pathogens or create new treatments for disease.
In biology, the binding of cellular proteins to molecules called ligands produces myriad functions essential for life, ...
Researchers have innovatively merged protein structural data with genetic sequences to construct evolutionary trees, ...
The three-dimensional shape of a protein can be used to resolve deep, ancient evolutionary relationships in the tree of life, ...
The three-dimensional shape of a protein can be used to resolve deep, ancient evolutionary relationships in the tree of life, ...
Proteins are biopolymers of amino acids (polypeptides), joined by peptide bonds, that are generated by ribosomes. The amino acid sequence, encoded by its gene, determines a protein’s structure ...
To overcome that limitation, MIT researchers have developed a computational technique that allows large language models to predict antibody structures more accurately. Their work could enable ...
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