Tau is a microtubule-associated protein that helps to stabilize the structure of neurons, specifically by supporting ...

This manuscript describes the identification and characterization of 12 specific phosphomimetic mutations in the recombinant full-length human tau protein that trigger tau to form fibrils. This ...

This is compared to approximately 3 billion base pairs on the human genome. Function: Mitochondrial DNA is crucial for the production of proteins involved in the electron transport chain and ATP ...

New study led by Prof Karen Duff, Dr Naoto Watamura, & Dr Martha Foiani (UK DRI at UCL) with Prof Takaomi Saido (Riken Center for Brain Science, Japan) reveals insight into the early stages of toxic ...

Altered cerebrospinal fluid (CSF) levels of amyloid-β (Aβ) and tau proteins have been found in PDD, with intermediate changes for Aβ42 in non-demented PD. The authors investigated whether AD-related ...

A study conducted by researchers at the Kennedy Institute of Rheumatology has uncovered a pivotal role of asparagine metabolism in regulating B cell homeostasis and immune response. Germinal ...

Proteins, the essential molecular machinery of life, play a central role in numerous biological processes. Decoding their intricate sequence, structure, and function (SSF) is a fundamental pursuit in ...

In their research published in Cell Reports, Shemesh and his international team discovered that when HSV-1 infects brain cells, it triggers an immune response involving a key protein called tau — the ...

Their new research has also revealed how tau protein may initially protect the brain from the virus but later contributes to brain damage. The findings are published in Cell Reports in an article ...

The study results are published today in Cell Reports. The study also revealed how tau protein, often viewed as harmful in Alzheimer’s, might initially protect the brain from the virus but ...