Researchers Discover Genetic Variant Associated With Earlier Onset Childhood Epilepsy Nov. 30, 2022 — Researchers have discovered a specific genetic variant in SCN1A, the most common genetic ...

“For example, people who have epilepsy caused by mutations in the gene SCN1A should not be prescribed sodium channel blockers, as this can make their epilepsy worse. Another example is ...

in the SCN1A gene. Zorevunersen is being developed as potentially BEDFORD, Mass., December 02, 2024--Stoke Therapeutics, Inc. (Nasdaq: STOK), a biotechnology company dedicated to restoring protein ...

For my senior project I worked with Dr. Joanna Mattis at the University of Michigan, and took a deep dive into understanding the relationship between EEG spikes and calcium dynamics in the brain, ...

Value-Creating Catalysts Anticipated Every Quarter in 2025: Q1 – FDA Decision on File Acceptance of Pitolisant sNDA for Idiopathic Hypersomnia; Potential Approval in 2025 Q2 – Orexin/BP1.15205 ...

Harmony Biosciences Holdings, Inc. today announced strong preliminary, unaudited net product revenues for Q4 and full year 2024 of $201 million and $714 million, respectively. Building on this ...

Jan. 22, 2025 — Doctors could soon reduce epilepsy misdiagnoses by up to 70% using a new tool that turns routine electroencephalogram, or EEG, tests that appear normal into highly accurate ...

Am J Health Syst Pharm. 2009;66(6):541-561. Shorvon et al. [20] conducted a multicenter, double-blind, randomized, placebo-controlled trial to evaluate the efficacy and tolerability of ...

Sigma 1 receptor (S1R) is a multifunctional, ligand-activated protein located in the membranes of the endoplasmic reticulum (ER). It mediates a variety of neurological disorders, including epilepsy, ...

Seizure medicines can affect the way the body handles antibiotics. But the reverse is also true: some antibiotics affect levels of seizure medicines. If you are taking doxycycline (Vibramycin) for ...

Introduction: Clinically relevant mutations to voltage-gated ion channels, called channelopathies, alter ion channel function, properties of ionic currents, and neuronal firing. The effects of ion ...