In their study, published in the journal Science Translational Medicine, the group found a certain conformation-specific antibody that would bind to tau proteins, placed it inside of a shell that ...

The concentrations of conformationally altered tau proteins in homogenized dissected areas of the brain were measured by ELISA using two different antibodies specific for tau protein alterations.

Merck & Co is looking to improve its neurology pipeline via a deal with Teijin Pharma to develop a new tau-targeting antibody. The tau protein is implicated in a number of nervous system ...

The team found that TTCM2 utilizes a naturally occurring protein in cells known as TRIM21, which functions as an intracellular antibody receptor – helping to mark the antibody-bound tau aggregates.

Scientists have only shifted focus more recently to developing anti-tau therapies. Of the tau aggregation inhibitors and antibodies that they have generated so far, many of them do not efficiently ...

Tau is a protein that is found in cells of the central ... Biogen and Eisai have already filed for approval of their amyloid-targeting antibody aducanumab, and while some analysts see the evidence ...

“P-Tau can increase three- to seven-fold ... to isolate individual immunocomplexes (consisting of an antibody-bound target protein and fluorescent reporter enzyme), boosting sensitivity at ...

Anti-tau candidates haven’t crossed the regulatory threshold like their anti-amyloid counterparts, but J&J’s clinical efforts ...

Many vaccines work by introducing a protein to the body that resembles part of a virus. Ideally, the immune system will ...

Tau is a microtubule-associated protein encoded by the MAPT gene located on chromosome 17q21. It promotes microtubule assembly and stability and may play a role in establishing and maintaining ...

The vaccine appeared to stimulate the immune systems of the mice, as their antibodies, which react with tau and remove protein, more than doubled compared to when no measures were taken.