Additionally, some of the therapeutic antibodies can cause serious side effects. Before I joined the group, the Eisenberg team used tau’s structure to design a six-residue, D-enantiomeric peptide ...

Tau protein is a microtubule-associated protein (MAP) known to stabilize the internal structure of neurons, binding to microtubules. These are microscopic tubular structures that support the ...

Figure 1: Direct and indirect pathological events that can contribute to tau-mediated neurodegeneration. Figure 2: The domain structure of the tau isoforms that are expressed in the adult human brain.

Exercise may positively influence the interactions between brain cells in the hippocampus, a brain region involved in ...

For each structural strain of tau fibrils, they identified amino acids without which the strain cannot form its signature ...

Acupuncture treatment on the DU channel has shown therapeutic effects for Alzheimer’s disease (AD), but the underlying mechanisms are not yet clear. The purpose of this study was to comprehensively ...