Background The use of biologic agents allows the application of precision medicine in the treatment of paediatric severe asthma. Aim To describe the real-life effectiveness of biologic agents in ...

Objectives Critical appraisal and evidence based medicine (EBM) are ‘academic’ skills that guide daily practice and drive improvements in patient care, and are thus essential components of the ...

Aims: To investigate long term effects of early adverse circumstances on cognitive function. Methods: Associations between early material home circumstances, parental divorce, maternal management and ...

On 20 February 2020, so-called Italian Patient 1 was admitted to the intensive care unit of his local hospital due to a deteriorating clinical condition from SARS-CoV-2/COVID-19 infection. In Italy, ...

Objective The aim of this research was to ascertain the effectiveness of current electronic prescribing (EP) systems to prevent a standardised set of paediatric prescribing errors likely to cause harm ...

One quarter of all adults in the UK are regular smokers, the vast majority having started smoking in their teens. Teenage smoking, especially in females, continues to increase both as regards the ...

Results 449 infants presented with acute bronchiolitis during the study period (298 (66%) male, mean age 23±14.5 weeks). 163 (36%) infants were admitted to hospital. The five best predictors of ...

Dental caries continues to be a serious problem. Affecting 2.4 billion people, it is the most prevalent disease worldwide.1 Although a highly prevalent condition, the impact of childhood dental caries ...

Background Children and their parents report poor sleep in hospital and complain about noise. Objective To measure sleep quality and noise levels in hospital and compare these with the home ...

Background When children and young people (CYP) report their own suspected adverse drug reactions (ADRs), different patterns of drugs and symptoms are noted. A new guide to reporting suspected ADRs ...

Objectives To provide up-to-date information on the use of long-term ventilation (LTV) in the UK paediatric population and to compare the results with data collected 10 and 20 years previously. Design ...

The investigation of global developmental delay in preschool children varies between centres and between paediatricians. [1] [1] Following a literature search and review of the evidence base, ...