Proteins are fundamental to life. They are involved in virtually every process within our bodies, from catalyzing chemical ...

Adhesion G protein-coupled receptors (GPCRs) are a group of cell-surface sensors associated with many body functions and diseases. However, they are not yet sufficiently understood to be exploited for ...

Researchers say strategy will help understand the history of life, monitor the spread of pathogens or create new treatments for disease.

In biology, the binding of cellular proteins to molecules called ligands produces myriad functions essential for life, ...

Researchers have innovatively merged protein structural data with genetic sequences to construct evolutionary trees, ...

In trials at University College London Hospitals (UCLH), an ASO is being used to target the mutated gene that results in the ...

Proteins are biopolymers of amino acids (polypeptides), joined by peptide bonds, that are generated by ribosomes. The amino acid sequence, encoded by its gene, determines a protein’s structure ...

To overcome that limitation, MIT researchers have developed a computational technique that allows large language models to predict antibody structures more accurately. Their work could enable ...

All living things contain proteins which are built from specific sequences of amino acids. While amino acid sequences are encoded in DNA sequences, it still is phylogenetically useful to also compare ...