Two new PET radiotracers have outperformed the only current Food and Drug Administration (FDA) approved radiotracer for ...

One of the most difficult aspects of developing treatments for Alzheimer’s disease is understanding the mechanisms of neuron death amid amyloid plaques, tau tangles and other forms of toxicity ...

The Amyloid—Tangle Connection. Aβ aggregates (green) hyper-excite neurons in tau epicenters and connected regions, strengthening that connectivity. This pushes tau propagation from one region to ...

Blood tests measured levels of other telling proteins, including phosphorylated tau and brain-derived neurotrophic factor (BDNF), which play crucial roles in brain health and disease. Sleeping ...

Those with Alzheimer’s were more likely to have delayed REM sleep, and they also tended to have higher levels of the two toxic proteins, amyloid, and tau, found in people with the condition. Those ...

In AD, the protein goes haywire, forming tangles that have been linked to cell damage and neuronal death. Tau tangles are one of the characteristic hallmarks of Alzheimer's visible in the brain ...

In AD, the protein goes haywire, forming tangles that have been linked to cell damage and neuronal death. Tau tangles are one of the characteristic hallmarks of Alzheimer's visible in the brain ...

Mapping a key protein in the brain in Alzheimer’s disease Researchers ... A PhD student at the University of Exeter will look at ways to reduce tau tangles by targeting immune cells in the brain. If ...