Joseph Arboleda-Velasquez of Harvard Medical School praised the results. “Ye’s group has now provided compelling evidence showing increased binding affinity of ApoE3 Christchurch for tau and its ...

Two new PET radiotracers have outperformed the only current Food and Drug Administration (FDA) approved radiotracer for ...

Because it can only be diagnosed with an autopsy, the neurodegenerative disease is difficult to pin in cases of professional ...

Chronic traumatic encephalopathy, or CTE, is a degenerative brain disease linked to repetitive head trauma. Here's how it affects the brain and who is most at risk.

The performance of neurodegenerative biomarkers—neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP), tau, and ubiquitin carboxy-terminal hydrolase L1 (UCHL1)—in diagnosing minimal ...

Amyloid plaques form between brain cells, disrupting communication, while tau tangles build up inside cells and cause damage. From dancing to taking 2p vitamins, the simple tweaks don’t have to ...

In the paper, the researchers describe how they examined how aerobic exercise impacted the development of amyloid plaques and tau tangles in the hippocampus brain region of rats, as well as the ...

The research focused on the hippocampus, the brain region responsible for memory and learning, and measured the impact of aerobic exercise on key Alzheimer's markers: amyloid plaques, tau tangles ...

The research focused on the hippocampus, the brain region responsible for memory and learning, and measured the impact of aerobic exercise on key Alzheimer’s markers: amyloid plaques, tau tangles, and ...

Most treatments being pursued today to protect against Alzheimer's disease focus on amyloid plaques and tau tangles that accumulate in the brain, but new research from Mass General Brigham and ...

This manuscript describes the identification and characterization of 12 specific phosphomimetic mutations in the recombinant full-length human tau protein that trigger tau to form fibrils. This ...