Introduction: Clinically relevant mutations to voltage-gated ion channels, called channelopathies, alter ion channel function, properties of ionic currents, and neuronal firing. The effects of ion ...

a severe genetic epilepsy often linked to SCN1A mutations. This designation, the third for relutrigine, reinforces the company’s commitment to addressing needs in rare neurological disorders.

This study provides valuable evidence for the mechanism underlying KCNC1-related developmental and epileptic encephalopathy. The authors have generated and characterized a new knock-in mouse with a ...

Background and Objectives: Developmental and epileptic encephalopathies (DEEs) are a group of neurological disorders characterized by early-onset seizures that are often resistant to treatment, by ...

The Seizure Recognition and First Aid certification training provides information to increase the knowledge, skills and confidence in recognizing seizures and safely administering seizure first aid.