Additionally, some of the therapeutic antibodies can cause serious side effects. Before I joined the group, the Eisenberg team used tau’s structure to design a six-residue, D-enantiomeric peptide ...

Tau protein is a microtubule-associated protein (MAP) known to stabilize the internal structure of neurons, binding to microtubules. These are microscopic tubular structures that support the ...

Figure 1: Direct and indirect pathological events that can contribute to tau-mediated neurodegeneration. Figure 2: The domain structure of the tau isoforms that are expressed in the adult human brain.

Exercise may positively influence the interactions between brain cells in the hippocampus, a brain region involved in ...

For each structural strain of tau fibrils, they identified amino acids without which the strain cannot form its signature ...