Notre Dame and Penn State are set for the College Football Playoff Orange Bowl semifinal with a shot at the national title matchup on the line. Here’s the latest prediction for the game from an expert analytical model that projects scores and picks winners.

The semifinals of the first-ever 12-team College Football Playoff begin Thursday with a blockbuster Orange Bowl matchup between (6) Penn State and (7) Notre Dame. Both teams have leaned heavily on their defenses and run games to reach the doorstep of the College Football Playoff National Championship.

Either the Irish or the Nittany Lions will look to book a trip to the Jan. 20 CFP national championship game at Mercedes-Benz Stadium in Atlanta.